Comparison

Method Jupyter Rmarkdown Quarto
IDE JupyterHub, JupyterLab R, Rstudio VS Code, Jupyter, Rstudio, Neovim, TextEditor
Code mixing Limited Yes Yes
Format ipynb Rmd Qmd, Rmd, ipynb
Output Asciidoc, HTML, LaTeX, MD, PDF, RST, Slide (Reveal) HTML, PDF, Docx, ODT, RTF, MD, Slides (Powerpoint, Reveal,...), Dashboard, ... HTML, PDF, Docx, ODT, Epub, RTF, MD, Slides (Powerpoint, Reveal,...), Wiki (MediaWiki, ...), Book, and more !
Reproductibility Easy Easy Yes (if done from the start)

And the winner is...